glutamic acid

Research use only, not for human use.

(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.

Glutamic Acid is a non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.

Cell Viability Assay Cell Line:SH-SY5Y, IMR-32, SK-N-BE(2)Concentration:2, 5, 10, 20 mM Incubation Time:24 and 48 h Result:Reduced cell viability in a dose-dependent manner.

Animal Model:Crv4 mice model Dosage:3 g/kg Administration:s.c., single dose Result:Reduced the number of Brn-3a+ RGCs by >70%.In the absence of mGlu1 receptor, MSG-induced retinal damage is diminished.Animal Model:CPF-induced rat model Dosage:750 mg/kg Administration:i.p.Result:Reduced CPF-induced oxidative stress by increasing the level of GSH and activity of GSH-related enzymes.

Glutamic Acid | Glutamicol | AI3-18472

Endocrinology/Hormones

Estrogen Receptor/ERR

Others

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56-86-0

147.13

C5H9NO4

>98% (HPLC)

In Vitro:?H2O : 6.25 mg/mL (42.48 mM)

C(CC(=O)O)C(C(=O)O)N

L-glutamic acid

(-20℃)

With Ice Pack

≥ 2 years